Does Tresiba cause weight gain? (2024)

FAQs

Does Tresiba cause weight gain? ›

Some people taking Tresiba may gain weight. In fact, weight gain is a common side effect of all insulins. It happens because of the way insulin works in your body. Insulin helps your liver, muscles, and fat cells remove excess sugar from your blood and store it for future use.

All types of insulin can lead to weight gain. However, studies show that insulin determir (Levemir) may lead to less weight gain than insulin glargine (Lantus) and intermediate-acting insulin.

Tresiba is available in 100 units per mL (U-100) and 200 units per mL (U-200) formulations. Common Tresiba side effects include hypoglycemia (low blood glucose), weight gain, and upper respiratory tract infections (URTIs) like the common cold. Injection site reactions may also occur.

Yes, weight gain is a common side effect of all insulins, including Tresiba and Lantus.

Insulin helps your liver, muscles, and fat cells remove excess sugar from your blood and store it for future use. Over time, this can lead to some weight gain. In clinical studies, people with type 1 diabetes gained an average of 4 pounds (lb), about 1.8 kilograms (kg), over 1 year of taking Tresiba.

Insulin-associated weight gain may result from a reduction of blood glucose to levels below the renal threshold without a compensatory reduction in calorie intake, a defensive or unconscious increase in calorie intake caused by the fear or experience of hypoglycaemia, or the 'unphysiological' pharmaco*kinetic and ...

Exercise seems to work off belly fat in particular because it reduces circulating levels of insulin —which would otherwise signal the body to hang on to fat—and causes the liver to use up fatty acids, especially those nearby visceral fat deposits, he says.

Sanofi has sued Novo over the Danish drugmaker's marketing materials for Tresiba, alleging that they falsely claimed Sanofi's competing products—blockbuster Lantus and follow-up Toujeo—won't be available to many U.S. patients down the line, Reuters reported.

Is Tresiba hard on the kidneys? ›

People with kidney or liver problems may have a higher risk for hypoglycemia while using Tresiba. Before using this drug, let your doctor know if you have a history of kidney or liver problems. They can recommend ways to help prevent hypoglycemia. Hypokalemia.

Tresiba doesn't work for everyone. Basaglar, Lantus, Levemir, Novolin, and Toujeo are some Tresiba alternatives. Get the full list here. With over 37 million Americans living with diabetes and 96 million categorized as pre-diabetic, improving glucose levels early and effectively can be a challenge.

The recommended starting dose of TRESIBA in insulin naïve patients with type 2 diabetes mellitus is 10 units once daily.

When you start insulin therapy and begin getting your blood sugar under control, the glucose in your body is absorbed and stored. This causes weight gain if the amount you eat is more than you need for the day.

Background: Weight gain often occurs when insulin therapy is initiated. The long-acting insulin analog insulin detemir has been shown to be effective and well tolerated when used in basal-bolus regimens or as an add-on to oral antidiabetic drugs (OADs) and causes less weight gain than other insulins.

In a large safety study vs Lantus^® in adults with type 2 diabetes and heart disease, Tresiba^® did not increase their risk of major cardiovascular events, such as heart attack, stroke, or death. Compared to Lantus^®, Tresiba^® also had a lower rate of severe low blood sugar, a possible serious side effect of insulin.

For adults with diabetes, Tresiba^® should be taken once daily, any time of day. While taking your insulin at the same time every day is recommended, if you miss or delay your Tresiba^® dose, simply take it as soon as you can, then return to your normal dosing schedule.

Do not reuse or share needles with other people because you may get a serious infection. Keep Tresiba out of the reach of children. Since this medicine may be kept in a refrigerator, take special precautions to keep it away from children who also use the refrigerator.